A key role for neuropeptide Y in lifespan extension and cancer suppression via dietary restriction

Knowledge of genes essential for the life-extending effect of dietary restriction (DR) in mammals is incomplete. In this study, we found that neuropeptide Y (Npy), which mediates physiological adaptations to energy deficits, is an essential link between DR and longevity in mice. The lifespan-prolong...

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Detalhes bibliográficos
Main Authors: Chiba, Takuya, Tamashiro, Yukari, Park, Daeui, Kusudo, Tatsuya, Fujie, Ryoko, Komatsu, Toshimitsu, Kim, Sang Eun, Park, Seongjoon, Hayashi, Hiroko, Mori, Ryoichi, Yamashita, Hitoshi, Chung, Hae Young, Shimokawa, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970128/
https://ncbi.nlm.nih.gov/pubmed/24682105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04517
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