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Monosaccharide digitoxin derivative sensitize human non-small cell lung cancer cells to anoikis through Mcl-1 proteasomal degradation

Advanced stage cancers acquire anoikis resistance which provides metastatic potential to invade and form tumors at distant sites. Suppression of anoikis resistance by novel molecular therapies would greatly benefit treatment strategies for metastatic cancers. Recently, digitoxin and several of its n...

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Hlavní autoři: Pongrakhananon, Varisa, Stueckle, Todd A., Wang, Hua-Yu Leo, O'Doherty, George A., Dinu, Cerasela Zoica, Chanvorachote, Pithi, Rojanasakul, Yon
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3970117/
https://ncbi.nlm.nih.gov/pubmed/24231508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.10.027
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