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Stereochemical Survey of Digitoxin Monosaccharides

[Image: see text] A stereochemically diverse array of monosaccharide analogues of the trisaccharide-based cardiac glycoside natural product digitoxin has been synthesized using a de novo asymmetric approach. The analogues were tested for cytotoxicity against the NCI panel of 60 human cancer cell lin...

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Bibliografiske detaljer
Main Authors: Wang, Hua-Yu Leo, Xin, Wenjun, Zhou, Maoquan, Stueckle, Todd A., Rojanasakul, Yon, O'Doherty, George A.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2010
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3105780/
https://ncbi.nlm.nih.gov/pubmed/21643465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100219d
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