Increased Severity of Tuberculosis in Guinea Pigs with Type 2 Diabetes: A Model of Diabetes-Tuberculosis Comorbidity

Impaired glucose tolerance and type 2 diabetes were induced in guinea pigs to model the emerging comorbidity of Mycobacterium tuberculosis infection in diabetic patients. Type 2 diabetes mellitus was induced by low-dose streptozotocin in guinea pigs rendered glucose intolerant by first feeding a hig...

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Main Authors: Podell, Brendan K., Ackart, David F., Obregon-Henao, Andres, Eck, Sarah P., Henao-Tamayo, Marcela, Richardson, Michael, Orme, Ian M., Ordway, Diane J., Basaraba, Randall J.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2014
Teme:
Regular Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969993/
https://ncbi.nlm.nih.gov/pubmed/24492198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.12.015
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