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Effects of two major activating lesions on the structure and conformation of human ras oncogene products.
ras oncogenes are frequently activated in human tumors by mutations at codon 12 or 61 in their coding sequences. To investigate how these subtle alterations exert such profound effects on the biologic activities of these genes, we studied structural and conformational properties of human ras-oncogen...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1985
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC396966/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3918304/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.1.38 |
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