Mechanism of activation of an N-ras oncogene of SW-1271 human lung carcinoma cells.

An N-ras-related transforming gene was detected in the human lung carcinoma cell line SW-1271 and molecularly cloned. The lesion responsible for its acquisition of transforming activity was localized to a single nucleotide transition from A to G in codon 61 of the predicted protein. This lesion in t...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Yuasa, Y, Gol, R A, Chang, A, Chiu, I M, Reddy, E P, Tronick, S R, Aaronson, S A
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1984
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345280/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6587382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.81.12.3670
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