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Cytochrome P450 Drives a HIF-regulated Behavioral Response to Reoxygenation by C. elegans
Oxygen deprivation followed by reoxygenation causes pathological responses in many disorders, including ischemic stroke, heart attacks and reperfusion injury. Key aspects of ischemia-reperfusion can be modeled by a C. elegans behavior, the O2-ON response, which is suppressed by hypoxic preconditioni...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3969381/ https://ncbi.nlm.nih.gov/pubmed/23811225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1235753 |
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