Development of a T Cell Receptor Targeting an HLA-A*0201 Restricted Epitope from the Cancer-Testis Antigen SSX2 for Adoptive Immunotherapy of Cancer

The clinical success of adoptive immunotherapy of cancer relies on the selection of target antigens that are highly expressed in tumor cells but absent in essential normal tissues. A group of genes that encode the cancer/testis or cancer germline antigens have been proposed as ideal targets for immu...

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Detalhes bibliográficos
Main Authors: Abate-Daga, Daniel, Speiser, Daniel E., Chinnasamy, Nachimuthu, Zheng, Zhili, Xu, Hui, Feldman, Steven A., Rosenberg, Steven A., Morgan, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969312/
https://ncbi.nlm.nih.gov/pubmed/24681846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0093321
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