Localization-Dependent and -Independent Roles of SLX4 in Regulating Telomeres

SLX4, a scaffold for structure-specific DNA repair nucleases, is important for several types of DNA repair. Many repair proteins bind to sites of DNA damage, resulting in subnuclear “foci,” but SLX4 forms foci in human cells even without DNA damage. Using several approaches, we show that most, but n...

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Bibliographische Detailangaben
Hauptverfasser: Wilson, Jamie S.J., Tejera, Agueda M., Castor, Dennis, Toth, Rachel, Blasco, Maria A., Rouse, John
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cell Press 2013
Schlagworte:
Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969258/
https://ncbi.nlm.nih.gov/pubmed/23994477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.07.033
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