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Localization-Dependent and -Independent Roles of SLX4 in Regulating Telomeres

SLX4, a scaffold for structure-specific DNA repair nucleases, is important for several types of DNA repair. Many repair proteins bind to sites of DNA damage, resulting in subnuclear “foci,” but SLX4 forms foci in human cells even without DNA damage. Using several approaches, we show that most, but n...

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Detalhes bibliográficos
Main Authors: Wilson, Jamie S.J., Tejera, Agueda M., Castor, Dennis, Toth, Rachel, Blasco, Maria A., Rouse, John
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969258/
https://ncbi.nlm.nih.gov/pubmed/23994477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.07.033
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