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Mec1/Tel1–dependent phosphorylation of Slx4 stimulates Rad1–Rad10 dependent cleavage of non–homologous DNA tails

Budding yeast Slx4 interacts with the Rad1–Rad10 endonuclease that is involved in nucleotide excision repair (NER), homologous recombination (HR) and single–strand annealing (SSA). We previously showed that Slx4 is dispensable for NER but is essential for SSA. Slx4 is phosphorylated by the Mec1 and...

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Detalhes bibliográficos
Publicado no:DNA Repair (Amst)
Main Authors: Toh, Geraldine W.-L., Sugawara, Neal, Dong, Junchao, Toth, Rachel, Lee, Sang Eun, Haber, James E., Rouse, John
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4352089/
https://ncbi.nlm.nih.gov/pubmed/20382573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2010.02.013
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