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Phosphorylation of Slx4 by Mec1 and Tel1 Regulates the Single-Strand Annealing Mode of DNA Repair in Budding Yeast

Budding yeast (Saccharomyces cerevisiae) Slx4 is essential for cell viability in the absence of the Sgs1 helicase and for recovery from DNA damage. Here we report that cells lacking Slx4 have difficulties in completing DNA synthesis during recovery from replisome stalling induced by the DNA alkylati...

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Detalhes bibliográficos
Main Authors: Flott, Sonja, Alabert, Constance, Toh, Geraldine W., Toth, Rachel, Sugawara, Neal, Campbell, David G., Haber, James E., Pasero, Philippe, Rouse, John
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2099619/
https://ncbi.nlm.nih.gov/pubmed/17636031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00135-07
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