Transcriptional regulation by nicotine in dopaminergic neurons

Dopaminergic neurons in the substantia nigra pars compacta (SNc) degenerate in Parkinson’s disease. These neurons robustly express several nicotinic acetylcholine receptor (nAChR) subtypes. Smoking appears to be neuroprotective for Parkinson’s disease but the mechanism is unknown. To determine wheth...

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Bibliographische Detailangaben
Hauptverfasser: Henley, Beverley M., Williams, Brian A., Srinivasan, Rahul, Cohen, Bruce N., Xiao, Cheng, Mackey, Elisha D.W., Wold, Barbara J., Lester, Henry A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969234/
https://ncbi.nlm.nih.gov/pubmed/23939186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.07.031
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