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Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT(1A) receptors without diminishing nervous system function or chemotherapy efficacy

BACKGROUND AND PURPOSE: Paclitaxel (PAC) is associated with chemotherapy-induced neuropathic pain (CIPN) that can lead to the cessation of treatment in cancer patients even in the absence of alternate therapies. We previously reported that chronic administration of the non-psychoactive cannabinoid c...

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Библиографические подробности
Главные авторы: Ward, Sara Jane, McAllister, Sean D, Kawamura, Rumi, Murase, Ryuchi, Neelakantan, Harshini, Walker, Ellen A
Формат: Artigo
Язык:Inglês
Опубликовано: British Journal of Pharmacology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969077/
https://ncbi.nlm.nih.gov/pubmed/24117398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12439
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