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Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT(1A) receptors without diminishing nervous system function or chemotherapy efficacy

BACKGROUND AND PURPOSE: Paclitaxel (PAC) is associated with chemotherapy-induced neuropathic pain (CIPN) that can lead to the cessation of treatment in cancer patients even in the absence of alternate therapies. We previously reported that chronic administration of the non-psychoactive cannabinoid c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ward, Sara Jane, McAllister, Sean D, Kawamura, Rumi, Murase, Ryuchi, Neelakantan, Harshini, Walker, Ellen A
Format: Artigo
Sprache:Inglês
Veröffentlicht: British Journal of Pharmacology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969077/
https://ncbi.nlm.nih.gov/pubmed/24117398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12439
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