Cannabidiol inhibits paclitaxel-induced neuropathic pain through 5-HT(1A) receptors without diminishing nervous system function or chemotherapy efficacy

BACKGROUND AND PURPOSE: Paclitaxel (PAC) is associated with chemotherapy-induced neuropathic pain (CIPN) that can lead to the cessation of treatment in cancer patients even in the absence of alternate therapies. We previously reported that chronic administration of the non-psychoactive cannabinoid c...

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Detalhes bibliográficos
Main Authors: Ward, Sara Jane, McAllister, Sean D, Kawamura, Rumi, Murase, Ryuchi, Neelakantan, Harshini, Walker, Ellen A
Formato: Artigo
Idioma:Inglês
Publicado em: British Journal of Pharmacology 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969077/
https://ncbi.nlm.nih.gov/pubmed/24117398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12439
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