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Effects of Cavities at the Nicotinamide Binding Site of Liver Alcohol Dehydrogenase on Structure, Dynamics and Catalysis

[Image: see text] A role for protein dynamics in enzymatic catalysis of hydrogen transfer has received substantial scientific support, but the connections between protein structure and catalysis remain to be established. Valine residues 203 and 207 are at the binding site for the nicotinamide ring o...

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Auteurs principaux: Yahashiri, Atsushi, Rubach, Jon K., Plapp, Bryce V.
Format: Artigo
Langue:Inglês
Publié: American Chemical Society 2014
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3969020/
https://ncbi.nlm.nih.gov/pubmed/24437493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi401583f
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