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Cancer quasispecies and stem-like adaptive aneuploidy

In this paper we develop a theoretical frame to understand self-regulation of aneuploidy rate in cancer and stem cells. This is accomplished building upon quasispecies theory, by leaving its formal mathematical structure intact, but by drastically changing the meaning of its objects. In particular,...

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Hlavní autoři: Napoletani, Domenico, Signore, Michele, Struppa, Daniele C
Médium: Artigo
Jazyk:Inglês
Vydáno: F1000Research 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968898/
https://ncbi.nlm.nih.gov/pubmed/24715964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-268.v1
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