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Cancer quasispecies and stem-like adaptive aneuploidy

In this paper we develop a theoretical frame to understand self-regulation of aneuploidy rate in cancer and stem cells. This is accomplished building upon quasispecies theory, by leaving its formal mathematical structure intact, but by drastically changing the meaning of its objects. In particular,...

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Detalhes bibliográficos
Main Authors: Napoletani, Domenico, Signore, Michele, Struppa, Daniele C
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968898/
https://ncbi.nlm.nih.gov/pubmed/24715964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.2-268.v1
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