Microbubble-Size Dependence of Focused Ultrasound-Induced Blood–Brain Barrier Opening in Mice In Vivo

The therapeutic efficacy of neurological agents is severely limited, because large compounds do not cross the blood–brain barrier (BBB). Focused ultrasound (FUS) sonication in the presence of microbubbles has been shown to temporarily open the BBB, allowing systemically administered agents into the...

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Detalhes bibliográficos
Main Authors: Choi, James J., Feshitan, Jameel A., Baseri, Babak, Wang, Shougang, Tung, Yao-Sheng, Borden, Mark A., Konofagou, Elisa E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968777/
https://ncbi.nlm.nih.gov/pubmed/19846365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TBME.2009.2034533
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