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A Quantitative Pressure and Microbubble-Size Dependence Study of Focused Ultrasound-Induced Blood-Brain Barrier Opening Reversibility in vivo Using MRI

Focused Ultrasound (FUS) in conjunction with the systemic administration of microbubbles has been shown to open the blood-brain barrier (BBB) selectively, non-invasively and reversibly. In this study, we investigate the dependence of the BBB opening’s reversibility on the peak-rarefactional pressure...

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Detalhes bibliográficos
Main Authors: Samiotaki, Gesthimani, Vlachos, Fotios, Tung, Yao-Sheng, Konofagou, Elisa E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3658823/
https://ncbi.nlm.nih.gov/pubmed/21858862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.23063
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