Microbubble-Size Dependence of Focused Ultrasound-Induced Blood–Brain Barrier Opening in Mice In Vivo

The therapeutic efficacy of neurological agents is severely limited, because large compounds do not cross the blood–brain barrier (BBB). Focused ultrasound (FUS) sonication in the presence of microbubbles has been shown to temporarily open the BBB, allowing systemically administered agents into the...

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Autores principales: Choi, James J., Feshitan, Jameel A., Baseri, Babak, Wang, Shougang, Tung, Yao-Sheng, Borden, Mark A., Konofagou, Elisa E.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968777/
https://ncbi.nlm.nih.gov/pubmed/19846365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/TBME.2009.2034533
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