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Ataluren as an agent for therapeutic nonsense suppression
The interplay of translation and mRNA turnover has helped unveil how the regulation of gene expression is a continuum in which events that occur during the “birth” of a transcript in the nucleus can have profound effects on subsequent steps in the cytoplasm. Exemplifying this continuum is nonsense-m...
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Main Authors: | , , , |
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Format: | Artigo |
Language: | Inglês |
Published: |
2012
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3968684/ https://ncbi.nlm.nih.gov/pubmed/23215857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-120611-144851 |
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