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Ataluren as an agent for therapeutic nonsense suppression

The interplay of translation and mRNA turnover has helped unveil how the regulation of gene expression is a continuum in which events that occur during the “birth” of a transcript in the nucleus can have profound effects on subsequent steps in the cytoplasm. Exemplifying this continuum is nonsense-m...

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Hlavní autoři: Peltz, Stuart W., Morsy, Manal, Welch, Ellen M., Jacobson, Allan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968684/
https://ncbi.nlm.nih.gov/pubmed/23215857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-med-120611-144851
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