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Cofactor analogue-induced chemical reactivation of endonuclease activity in a DNA cleavage/methylation deficient TspGWI N(473)A variant in the NPPY motif

We reported previously that TspGWI, a prototype enzyme of a new Thermus sp. family of restriction endonucleases-methyltransferases (REases-MTases), undergoes the novel phenomenon of sinefungin (SIN)-caused specificity transition. Here we investigated mutant TspGWI N(473)A, containing a single amino...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Zylicz-Stachula, Agnieszka, Jeżewska-Frąckowiak, Joanna, Skowron, Piotr M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Springer Netherlands 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968444/
https://ncbi.nlm.nih.gov/pubmed/24442320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-014-3085-x
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