IRE1α is essential for Xenopus pancreas development

Inositol requiring enzyme-1 (IRE1) is highly conserved from yeasts to humans. Upon the endoplasmic reticulum (ER) stress, IRE1 activates X-box-binding protein 1 (XBP1) by unconventionally splicing XBP1 mRNA, which activates the unfolded protein response (UPR) to restore ER homeostasis. In mice, IRE1...

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Detalhes bibliográficos
Main Authors: Yuan, Li, Li, Xinxin, Feng, Jiaojiao, Yin, Chenyang, Yuan, Fang, Wang, Xinru
Formato: Artigo
Idioma:Inglês
Publicado em: Editorial Department of Journal of Biomedical Research 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968283/
https://ncbi.nlm.nih.gov/pubmed/24683410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7555/JBR.28.20130076
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