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AKAP79, PKC, PKA and PDE4 participate in a G(q)-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complex

AC2 (adenylate cyclase 2) is stimulated by activation of G(q)-coupled muscarinic receptors through PKC (protein kinase C) to generate localized cAMP in HEK (human embryonic kidney)-293 cells. In the present study, we utilized a sensitive live-cell imaging technique to unravel the proteins that play...

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Detalhes bibliográficos
Main Authors: Shen, Jia X., Cooper, Dermot M. F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968274/
https://ncbi.nlm.nih.gov/pubmed/23889134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20130359
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