Chargement en cours...

A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8–AKAP79–PKA signalling complex

Adenylyl cyclase (AC) isoforms can participate in multimolecular signalling complexes incorporating A-kinase anchoring proteins (AKAPs). We recently identified a direct interaction between Ca(2+)-sensitive AC8 and plasma membrane-targeted AKAP79/150 (in cultured pancreatic insulin-secreting cells an...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Willoughby, Debbie, Halls, Michelle L., Everett, Katy L., Ciruela, Antonio, Skroblin, Philipp, Klussmann, Enno, Cooper, Dermot M. F.
Format: Artigo
Langue:Inglês
Publié: The Company of Biologists 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3575714/
https://ncbi.nlm.nih.gov/pubmed/22976297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.111427
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!