Crk Adaptors Negatively Regulate Actin Polymerization in Pedestals Formed by Enteropathogenic Escherichia coli (EPEC) by Binding to Tir Effector

Infections by enteropathogenic Escherichia coli (EPEC) cause diarrhea linked to high infant mortality in developing countries. EPEC adheres to epithelial cells and induces the formation of actin pedestals. Actin polymerization is driven fundamentally through signaling mediated by Tir bacterial effec...

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Main Authors: Nieto-Pelegrin, Elvira, Meiler, Eugenia, Martín-Villa, José Manuel, Benito-León, María, Martinez-Quiles, Narcisa
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968158/
https://ncbi.nlm.nih.gov/pubmed/24675776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004022
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