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Crk Adaptors Negatively Regulate Actin Polymerization in Pedestals Formed by Enteropathogenic Escherichia coli (EPEC) by Binding to Tir Effector

Infections by enteropathogenic Escherichia coli (EPEC) cause diarrhea linked to high infant mortality in developing countries. EPEC adheres to epithelial cells and induces the formation of actin pedestals. Actin polymerization is driven fundamentally through signaling mediated by Tir bacterial effec...

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Main Authors: Nieto-Pelegrin, Elvira, Meiler, Eugenia, Martín-Villa, José Manuel, Benito-León, María, Martinez-Quiles, Narcisa
格式: Artigo
語言:Inglês
出版: Public Library of Science 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968158/
https://ncbi.nlm.nih.gov/pubmed/24675776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004022
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