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Crk Adaptors Negatively Regulate Actin Polymerization in Pedestals Formed by Enteropathogenic Escherichia coli (EPEC) by Binding to Tir Effector

Infections by enteropathogenic Escherichia coli (EPEC) cause diarrhea linked to high infant mortality in developing countries. EPEC adheres to epithelial cells and induces the formation of actin pedestals. Actin polymerization is driven fundamentally through signaling mediated by Tir bacterial effec...

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Autors principals: Nieto-Pelegrin, Elvira, Meiler, Eugenia, Martín-Villa, José Manuel, Benito-León, María, Martinez-Quiles, Narcisa
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968158/
https://ncbi.nlm.nih.gov/pubmed/24675776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004022
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