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Identification of New IκBα Complexes by an Iterative Experimental and Mathematical Modeling Approach
The transcription factor nuclear factor kappa-B (NFκB) is a key regulator of pro-inflammatory and pro-proliferative processes. Accordingly, uncontrolled NFκB activity may contribute to the development of severe diseases when the regulatory system is impaired. Since NFκB can be triggered by a huge va...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3967930/ https://ncbi.nlm.nih.gov/pubmed/24675998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003528 |
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