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Identification of New IκBα Complexes by an Iterative Experimental and Mathematical Modeling Approach

The transcription factor nuclear factor kappa-B (NFκB) is a key regulator of pro-inflammatory and pro-proliferative processes. Accordingly, uncontrolled NFκB activity may contribute to the development of severe diseases when the regulatory system is impaired. Since NFκB can be triggered by a huge va...

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Detalhes bibliográficos
Main Authors: Konrath, Fabian, Witt, Johannes, Sauter, Thomas, Kulms, Dagmar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967930/
https://ncbi.nlm.nih.gov/pubmed/24675998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003528
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