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Mechanism of PP2A-mediated IKKβ dephosphorylation: a systems biological approach

BACKGROUND: Biological effects of nuclear factor-κB (NFκB) can differ tremendously depending on the cellular context. For example, NFκB induced by interleukin-1 (IL-1) is converted from an inhibitor of death receptor induced apoptosis into a promoter of ultraviolet-B radiation (UVB)-induced apoptosi...

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Bibliografische gegevens
Hoofdauteurs: Witt, Johannes, Barisic, Sandra, Schumann, Eva, Allgöwer, Frank, Sawodny, Oliver, Sauter, Thomas, Kulms, Dagmar
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2727496/
https://ncbi.nlm.nih.gov/pubmed/19607706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-3-71
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