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Advances in Methods to Characterize Ligand-Induced Ionic Lock and Rotamer Toggle Molecular Switch in G Protein-Coupled Receptors

Structural biology of GPCRs has made significant progress upon recently developed technologies for GPCRs expression/purification and elucidation of GPCRs crystal structures. The crystal structures provide a snapshot of the receptor structural disposition of GPCRs itself or with cocrystallized ligand...

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Bibliografische gegevens
Hoofdauteurs: Xie, Xiang-Qun, Chowdhury, Ananda
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967763/
https://ncbi.nlm.nih.gov/pubmed/23332699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-391861-1.00007-1
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