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3-Ketone-4,6-diene ceramide analogs exclusively induce apoptosis in chemo-resistant cancer cells

Multidrug-resistance is a major cause of cancer chemotherapy failure in clinical treatment. Evidence shows that multidrug-resistant cancer cells are as sensitive as corresponding regular cancer cells under the exposure to anticancer ceramide analogs. In this work we designed five new ceramide analog...

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Detalhes bibliográficos
Main Authors: Ponnapakam, Adharsh P., Liu, Jiawang, Bhinge, Kaustubh N., Drew, Barbara A., Wang, Tony L., Antoon, James W., Nguyen, Thong T., Dupart, Patrick S., Wang, Yuji, Zhao, Ming, Liu, Yong-Yu, Foroozesh, Maryam, Beckman, Barbara S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967587/
https://ncbi.nlm.nih.gov/pubmed/24457089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.12.065
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