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TP53 Promoter Methylation in Primary Glioblastoma: Relationship with TP53 mRNA and Protein Expression and Mutation Status

Reduced expression of TP53 by promoter methylation has been reported in several neoplasms. It remains unclear whether TP53 promoter methylation is associated with reduced transcriptional and protein expression in glioblastoma (GB). The aim of our work was to study the impact of TP53 methylation and...

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Main Authors: Jesionek-Kupnicka, Dorota, Szybka, Malgorzata, Malachowska, Beata, Fendler, Wojciech, Potemski, Piotr, Piaskowski, Sylwester, Jaskolski, Dariusz, Papierz, Wielislaw, Skowronski, Wieslaw, Och, Waldemar, Kordek, Radzislaw, Zawlik, Izabela
格式: Artigo
語言:Inglês
出版: Mary Ann Liebert, Inc. 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967380/
https://ncbi.nlm.nih.gov/pubmed/24506545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2013.2201
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