Ecto-5′-Nucleotidase (CD73) Regulates Host Inflammatory Responses and Exacerbates Murine Salmonellosis

Food-borne Salmonella spp., are a major cause of hospitalization and death. Adenosine, an important immune regulator of inflammation, limits tissue damage during infection. CD39 (nucleoside triphosphate dephosphorylase) combined with ecto-5′-nucleotidase (CD73) metabolizes ATP to adenosine. We studi...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Alam, M. Samiul, Kuo, Jennifer L., Ernst, Peter B., Derr-Castillo, Victoria, Pereira, Marion, Gaines, Dennis, Costales, Matthew, Bigley, Elmer, Williams, Kristina
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2014
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967249/
https://ncbi.nlm.nih.gov/pubmed/24670982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep04486
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky