Neurovascular protection by post-ischemic intravenous injections of the lipoxin A(4) receptor agonist, BML-111, in a rat model of ischemic stroke

Resolution of inflammation is an emerging new strategy to reduce damage following ischemic stroke. Lipoxin A(4) (LXA(4)) is an anti-inflammatory, pro-resolution lipid mediator with high affinity binding to its receptor ALX. Since LXA(4) is rapidly inactivated, potent analogs have been created, inclu...

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Main Authors: Hawkins, Kimberly E., DeMars, Kelly M., Singh, Jonathan, Yang, Changjun, Cho, Henry S., Frankowski, Jan C., Doré, Sylvain, Candelario-Jalil, Eduardo
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967241/
https://ncbi.nlm.nih.gov/pubmed/24225006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12607
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