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The invariant system of coordinates of antibody molecules: prediction of the "standard" C alpha framework of VL and VH domains.

A new approach of comparing protein structures that does not involve the procedure of superposition is suggested. An invariant system of coordinates for immunoglobulin molecules that is based on the geometrical symmetry inherent to the variable domain light-chain (VL)-heavy-chain (VH) complex is des...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Gelfand, I M, Kister, A E, Leshchiner, D
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1996
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39670/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622995/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3675
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