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Allosteric effects of erythromycin pretreatment on thioridazine block of hERG potassium channels
BACKGROUND AND PURPOSE: The prevalence of concurrent use of two or more drugs that block human ether-a-go-go-related gene product (hERG) K(+) channels is not uncommon, but is not well characterized. This study defined the effects of concurrent exposure of two hERG-blocking drugs on hERG current ampl...
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| Formato: | Artigo |
| Idioma: | Inglês |
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Blackwell Publishing Ltd
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3966747/ https://ncbi.nlm.nih.gov/pubmed/24417241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12575 |
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