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Hepatic insulin receptor deficiency impairs the SREBP-2 response to feeding and statins
The liver plays a central role in metabolism and mediating insulin action. To dissect the effects of insulin on the liver in vivo, we have studied liver insulin receptor knockout (LIRKO) mice. Because LIRKO livers lack insulin receptors, they are unable to respond to insulin. Surprisingly, the most...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Biochemistry and Molecular Biology
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3966700/ https://ncbi.nlm.nih.gov/pubmed/24516236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M043711 |
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