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Safety and Serological Response to a Matrix Gene-deleted Rabies Virus-based Vaccine Vector in Dogs

Dogs account for the majority of human exposures and deaths due to rabies virus (RABV) worldwide. In this report, we show that a replication-deficient RABV-based vaccine in which the matrix gene is deleted (RABV- M) is safe and induces rapid and potent VNA titers after a single inoculation in dogs....

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Detalhes bibliográficos
Main Authors: McGettigan, James P., David, Frederic, Figueiredo, Monica Dias, Minke, Jules, Mebatsion, Teshome, Schnell, Matthias J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966478/
https://ncbi.nlm.nih.gov/pubmed/24508037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.01.043
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