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Safety and Serological Response to a Matrix Gene-deleted Rabies Virus-based Vaccine Vector in Dogs
Dogs account for the majority of human exposures and deaths due to rabies virus (RABV) worldwide. In this report, we show that a replication-deficient RABV-based vaccine in which the matrix gene is deleted (RABV- M) is safe and induces rapid and potent VNA titers after a single inoculation in dogs....
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3966478/ https://ncbi.nlm.nih.gov/pubmed/24508037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.01.043 |
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