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Characterization of a Single-Cycle Rabies Virus-Based Vaccine Vector

Recombinant rabies virus (RV)-based vectors have demonstrated their efficacy in generating long-term, antigen-specific immune responses in murine and monkey models. However, replication-competent viral vectors pose significant safety concerns due to vector pathogenicity. RV pathogenicity is largely...

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Bibliografiske detaljer
Main Authors: Gomme, Emily A., Faul, Elizabeth J., Flomenberg, Phyllis, McGettigan, James P., Schnell, Matthias J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2826042/
https://ncbi.nlm.nih.gov/pubmed/20053743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01870-09
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