Second-Generation Rabies Virus-Based Vaccine Vectors Expressing Human Immunodeficiency Virus Type 1 Gag Have Greatly Reduced Pathogenicity but Are Highly Immunogenic

Rabies virus (RV) vaccine strain-based vectors show great promise as vaccines against other viral diseases such as human immunodeficiency virus type 1 (HIV-1) infection and hepatitis C, but a low residual pathogenicity remains a concern for their use. Here we describe several highly attenuated secon...

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Main Authors: McGettigan, James P., Pomerantz, Roger J., Siler, Catherine A., McKenna, Philip M., Foley, Heather D., Dietzschold, B., Schnell, Matthias J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Vaccines and Antiviral Agents
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC140592/
https://ncbi.nlm.nih.gov/pubmed/12477829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.1.237-244.2003
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