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Immune Modulating Effect by a Phosphoprotein-deleted Rabies Virus Vaccine Vector Expressing Two Copies of the Rabies Virus Glycoprotein Gene

The type of immune response induced by a vaccine is a critical factor that determines its effectiveness in preventing infection or disease. Inactivated and live rabies virus (RV) vaccine strains elicit an IgG1-biased and IgG1/IgG2a-balanced antibody response, respectively. However, IgG2a antibodies...

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Autors principals: Cenna, Jonathan, Tan, Gene S., Papaneri, Amy B., Dietzschold, Bernhard, Schnell, Matthias J., McGettigan, James P.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2629409/
https://ncbi.nlm.nih.gov/pubmed/18804506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2008.08.069
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