Amplification of AKT2 in human pancreatic cells and inhibition of AKT2 expression and tumorigenicity by antisense RNA.

We previously demonstrated that the putative oncogene AKT2 is amplified and overexpressed in some human ovarian carcinomas. We have now identified amplification of AKT2 in approximately 10% of pancreatic carcinomas (2 of 18 cell lines and 1 of 10 primary tumor specimens). The two cell lines with alt...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Cheng, J Q, Ruggeri, B, Klein, W M, Sonoda, G, Altomare, D A, Watson, D K, Testa, J R
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39663/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8622988/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.8.3636
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