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PAH clearance after renal ischemia and reperfusion is a function of impaired expression of basolateral Oat1 and Oat3

Determination of renal plasma flow (RPF) by para‐aminohippurate (PAH) clearance leads to gross underestimation of this respective parameter due to impaired renal extraction of PAH after renal ischemia and reperfusion injury. However, no mechanistic explanation for this phenomenon is available. Based...

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Detalhes bibliográficos
Main Authors: Bischoff, Ariane, Bucher, Michael, Gekle, Michael, Sauvant, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Periodicals, Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3966241/
https://ncbi.nlm.nih.gov/pubmed/24744908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/phy2.243
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