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Telomerase deficiency delays renal recovery in mice after ischemia reperfusion injury by impairing autophagy

The aged population suffers increased morbidity and higher mortality in response to episodes of acute kidney injury (AKI). Aging is associated with telomere shortening, and both telomerase reverse transcriptase (TerT) and RNA (TerC) are essential to maintain telomere length. To define a role of telo...

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Détails bibliographiques
Publié dans:Kidney Int
Auteurs principaux: Cheng, Huifang, Fan, Xiaofeng, Lawson, William E., Paueksakon, Paisit, Harris, Raymond C.
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490111/
https://ncbi.nlm.nih.gov/pubmed/25760322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.69
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