Telomerase deficiency delays renal recovery in mice after ischemia reperfusion injury by impairing autophagy

The aged population suffers increased morbidity and higher mortality in response to episodes of acute kidney injury (AKI). Aging is associated with telomere shortening, and both telomerase reverse transcriptase (TerT) and RNA (TerC) are essential to maintain telomere length. To define a role of telo...

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Bibliografiske detaljer
Udgivet i:Kidney Int
Main Authors: Cheng, Huifang, Fan, Xiaofeng, Lawson, William E., Paueksakon, Paisit, Harris, Raymond C.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490111/
https://ncbi.nlm.nih.gov/pubmed/25760322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2015.69
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