Rosiglitazone Affects Nitric Oxide Synthases and Improves Renal Outcome in a Rat Model of Severe Ischemia/Reperfusion Injury

Background. Nitric oxide (NO)-signal transduction plays an important role in renal ischemia/reperfusion (I/R) injury. NO produced by endothelial NO-synthase (eNOS) has protective functions whereas NO from inducible NO-synthase (iNOS) induces impairment. Rosiglitazone (RGZ), a peroxisome proliferator...

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Autors principals: Betz, Boris, Schneider, Reinhard, Kress, Tobias, Schick, Martin Alexander, Wanner, Christoph, Sauvant, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289925/
https://ncbi.nlm.nih.gov/pubmed/22448163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/219319
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