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Organic small hairpin RNAs (OshR): a Do-It-Yourself platform for transgene-based gene silencing
The RNA interference (RNAi) pathway in animal cells can be harnessed to silence gene expression with artificial small interfering RNAs (siRNAs) or transgenes that express small hairpin RNAs (shRNAs). The transgene-expressing shRNA approach has been adapted into large-scale resources for genome-wide...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3966114/ https://ncbi.nlm.nih.gov/pubmed/23707624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2013.05.007 |
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